Anti-CASP3 Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-07-11
產(chǎn)品詳請(qǐng)
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號(hào) |
K101291P
|
應(yīng)用范圍 |
WB IHC
|
CAS編號(hào) |
|
抗體名 |
Anti-CASP3 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點(diǎn) |
GSK3 alpha
|
適應(yīng)物種 |
Human Mouse
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識(shí)物 |
CPP32;CPP32B;SCA-1;SREBP cleavage activity 1;Cysteine protease CPP32
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human CASP3
|
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.