Anti-ITA2B Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-07-11
產(chǎn)品詳請
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K106413P
|
應(yīng)用范圍 |
WB
|
CAS編號 |
|
抗體名 |
Anti-ITA2B Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點(diǎn) |
MKP1
|
適應(yīng)物種 |
Human
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識物 |
ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human ITA2B
|
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.