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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-IL12 Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號:K106473P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-07-11
產(chǎn)品詳請
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K106473P
應(yīng)用范圍 WB
CAS編號
抗體名 Anti-IL12 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點 TTC8
適應(yīng)物種 Human Mouse Rat
形態(tài)
宿主 Rabbit
亞型 IgG
標識物 IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A
濃度 %
免疫原 A synthetic peptide of human IL12
IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
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