Anti-IL12 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-07-11
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K106473P
|
| 應(yīng)用范圍 |
WB
|
| CAS編號 |
|
| 抗體名 |
Anti-IL12 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
TTC8
|
| 適應(yīng)物種 |
Human Mouse Rat
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標識物 |
IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human IL12
|
IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
