Anti-XBP1 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-07-11
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K106477P
|
| 應用范圍 |
WB
|
| CAS編號 |
|
| 抗體名 |
Anti-XBP1 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
TRAPPC1
|
| 適應物種 |
Human Mouse Rat
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標識物 |
TREB-5;XBP2;TREB5;XBP-1;
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human XBP1
|
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1).
