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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-NQO1 Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號:K106519P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-07-11
產(chǎn)品詳請
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K106519P
應(yīng)用范圍 WB
CAS編號
抗體名 Anti-NQO1 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點
適應(yīng)物種 Human Mouse Rat
形態(tài)
宿主 Rabbit
亞型 IgG
標(biāo)識物 DHQU;DIA4;DTD;n MOR1;n MORI;QR1
濃度 %
免疫原 A synthetic peptide of human NQO1
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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