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北京索萊寶科技有限公司
產品展廳
Anti-XIAP Polyclonal Antibody
  • 品牌:Solarbio
  • 產地:北京
  • 貨號:K106527P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-07-11
產品詳請
產地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K106527P
應用范圍 WB
CAS編號
抗體名 Anti-XIAP Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點
適應物種 Human Mouse Rat
形態(tài)
宿主 Rabbit
亞型 IgG
標識物 API3;BIRC4;hIAP-3;hIAP3;IAP-3;ILP1;MIHA;XLP2
濃度 %
免疫原 A synthetic peptide of human XIAP
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
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