Anti-XIAP Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-07-11
產品詳請
產地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K106527P
|
應用范圍 |
WB
|
CAS編號 |
|
抗體名 |
Anti-XIAP Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點 |
|
適應物種 |
Human Mouse Rat
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標識物 |
API3;BIRC4;hIAP-3;hIAP3;IAP-3;ILP1;MIHA;XLP2
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human XIAP
|
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.