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| 產(chǎn)地 | 北京 |
| 品牌 | Solarbio |
| 貨號 | K106557P |
| 保存條件 | Store at -20°C. Avoid freeze / thaw cycles. |
| 用途 | 抗體 |
| 應(yīng)用范圍 | WB |
| 抗原來源 | 現(xiàn)詢客服 |
| CAS編號 | |
| 保質(zhì)期 | 現(xiàn)詢客服 |
| 抗體名 | Anti-AKT1+2+3 Polyclonal Antibody |
| 是否單克隆 | |
| 克隆性 | |
| 靶點 | |
| 適應(yīng)物種 | Human Mouse Rat |
| 形態(tài) | 干粉 |
| 宿主 | Rabbit |
| 標(biāo)記物 | 現(xiàn)詢客服 |
| 包裝規(guī)格 | 100ul |
| 純度 | 現(xiàn)詢客服% |
| 亞型 | IgG |
| 標(biāo)識物 | AKT;CWS6;PKB;PKB-ALPHA;PRKBA;RAC;RAC-ALPHA |
| 濃度 | % |
| 免疫原 | A synthetic peptide of human AKT1+2+3 |
| 是否進(jìn)口 |
英文名稱Anti-AKT1+2+3 Polyclonal Antibody
宿主Rabbit
別名AKT;CWS6;PKB;PKB-ALPHA;PRKBA;RAC;RAC-ALPHA
應(yīng)用WB稀釋比例
WB 1:3000.
交叉反應(yīng)Human Mouse Rat
蛋白分子量65kDaGene ID207
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human AKT1+2+3
性狀液體Public Immunogen RangeA synthetic peptide of human AKT1+2+3Subcellular LocationsCell membrane Cytoplasm NucleusSwiss ProtP31749
*類型Polyclonal Antibody
背景資料The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
