Anti-GAD65 Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-07-11
產(chǎn)品詳請
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K106572P
|
應(yīng)用范圍 |
WB IHC
|
CAS編號 |
|
抗體名 |
Anti-GAD65 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點 |
|
適應(yīng)物種 |
Human Mouse Rat
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識物 |
GAD2;DCE2;MGC161605;MGC161607
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human GAD65
|
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.