Anti-TLR4 Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-07-11
產(chǎn)品詳請
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K106584P
|
應(yīng)用范圍 |
WB
|
CAS編號 |
|
抗體名 |
Anti-TLR4 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點 |
|
適應(yīng)物種 |
Human Mouse Rat
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識物 |
ARMD10;CD284;TLR-4;TOLL
|
濃度 |
%
|
免疫原 |
Recombinant protein of human TLR4
|
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.