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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-KRT18 Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號(hào):K106590P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-07-11
產(chǎn)品詳請(qǐng)
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號(hào) K106590P
應(yīng)用范圍 WB IHC
CAS編號(hào)
抗體名 Anti-KRT18 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點(diǎn)
適應(yīng)物種 Human Mouse Rat
形態(tài)
宿主 Rabbit
亞型 IgG
標(biāo)識(shí)物 CK-18;CYK18;K18;PIG46;Cytokeratin-18
濃度 %
免疫原 Recombinant protein of human KRT18
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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