Anti-LIFR Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-07-11
產(chǎn)品詳請
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K106613P
|
應(yīng)用范圍 |
WB
|
CAS編號 |
|
抗體名 |
Anti-LIFR Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點(diǎn) |
|
適應(yīng)物種 |
Human
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識物 |
CD118;LIF-R;SJS2;STWS;SWS
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human LIFR
|
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.