Anti-MADH7 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-07-10
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K106646P
|
| 應(yīng)用范圍 |
IHC
|
| CAS編號 |
|
| 抗體名 |
Anti-MADH7 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點(diǎn) |
|
| 適應(yīng)物種 |
Human
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標(biāo)識物 |
CRCS3;MADH7;MADH8;Hsmad7；MAD homolog 8
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human MADH7
|
Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
