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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-TRF1 Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號:K107057P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-07-08
產(chǎn)品詳請
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K107057P
應(yīng)用范圍 IHC
CAS編號
抗體名 Anti-TRF1 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點(diǎn)
適應(yīng)物種 Human
形態(tài)
宿主 Rabbit
亞型 IgG
標(biāo)識物 Telomeric repeat-binding factor;1PIN2;TRBF1;TRF;TRF1
濃度 %
免疫原 A synthetic peptide of human TRF1
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
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