Anti-Tbx21 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-07-07
產品詳請
| 產地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K106901P
|
| 應用范圍 |
WB IHC
|
| CAS編號 |
|
| 抗體名 |
Anti-Tbx21 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
|
| 適應物種 |
Human Mouse
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標識物 |
TBET;TBLYM;T-box protein 21;Transcription factor TBLYM
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human Tbx21
|
Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs . Activates transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. Activates IFNG and CXCR3 genes in part by recruiting chromatin remodeling complexes including KDM6B, a SMARCA4-containing SWI/SNF-complex, and an H3K4me2-methyltransferase complex to their promoters and all of these complexes serve to establish a more permissive chromatin state conducive with transcriptional activation (By similarity).?
