Anti-E2F5 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-07-07
產(chǎn)品詳請(qǐng)
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號(hào) |
K107154P
|
| 應(yīng)用范圍 |
WB IHC
|
| CAS編號(hào) |
|
| 抗體名 |
Anti-E2F5 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點(diǎn) |
|
| 適應(yīng)物種 |
Human Mouse Rat
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標(biāo)識(shí)物 |
E2F-5;transcription factor E2F5
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human E2F5
|
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.
